Fenben, also known as fenbucon, is a medication used to treat parasites and worms in animals. It’s currently being touted as a cancer treatment in the “Joe Tippens Protocol”.
Researchers have found that fenben disrupts microtubules and interferes with glucose uptake, causing cancer cells to die. But this is not enough evidence to show that fenben can cure cancer.
Anti-cancer
Scientists have found that fenbendazole, a drug used to treat parasitic worms in animals like horses, may also be useful as an anti-cancer treatment. The drug acts by interfering with the formation of microtubules, a protein scaffold that provides shape and structure to cells. It has also been shown to interfere with cytoplasmic transport of organelles and cargoes.
These findings suggest that fenbendazole could be an effective cancer therapy, particularly for patients with lung cancer whose tumors are resistant to established treatments. Developing new drugs takes a significant amount of time and money, so repurposing existing veterinary medicines that show promise for human use can reduce development costs.
Anti-parasitic
Fenbendazole is a medication used to treat parasites and worms (roundworms, hookworms, whipworms, and some tapeworms) in animals. It is also being used as part of a cancer treatment protocol known as the Joe Tippens Protocol. It has not been shown to cure cancer in humans, but it can help slow down the spread of cancer.
A study published in 2021 found that fenbendazole, and other drugs like it, suppressed cancer cells in the lab (in vitro). It works by blocking the proper growth of microtubules. These are important structures that provide structure to all cells, including cancer cells.
Anti-helminthic
Fenbendazole is a broad-spectrum benzimidazole carbamate antiparasitic drug that has been in use as an anthelmintic for nearly six decades. This group of drugs, known as anthelmintics or vermifuges, expel parasitic worms from the body by stunning them or killing them without harming the host.
Mebendazole (MBZ) and other benzimidazole anti-helminthic drugs like albendazole, flubendazole, and oxfendazole are often prescribed for trematode and nematode infections in humans and animals. These drugs have been shown to be effective in treating helminths by binding to tubulin and disrupting the microtubule equilibrium. However, their limited absorption from the intestines results in low levels of drug in the tissues.
Anti-tumor
Fenbendazole, also known as Pancur, is an animal anthelmintic used to treat parasites and worms in animals (roundworms, hookworms, whipworms, and some tapeworms). It was recently discovered that it has powerful anti-cancer properties in humans. It is the primary ingredient in a cancer treatment protocol called the Joe Tippens Protocol.
Fenbendazole causes preferential elimination of cancer cells in vitro and in vivo through mild microtubule depolymerization and p53 activation with apoptosis and autophagy induction. It also inhibits glucose uptake in cancer cells through downregulation of GLUT transporters. Moreover, it induces ferroptosis in the cells via downregulation of GPX4. The combination of these pathways results in synergistic apoptosis in cancer cells.
Anti-viral
Fenbendazole is a broad-spectrum benzimidazole antihelminthic drug that is used to treat infections caused by worms. Its primary use is to prevent pinworms, but it has also been shown to be effective against cancer in animals.
Using a virus-induced cellular phenotype profiling approach, we show that fenbendazole can significantly inhibit the productive infection of BoHV-1 in MDBK cells. This effect was observed at both the early and late stages of the viral replication cycle. In addition, fenbendazole inhibited the expression of viral tegument protein VP16 in MDBK cells. It did not, however, affect the PLC-g1/Akt cascade stimulated by BoHV-1 infection.
Anti-inflammatory
Fenbendazole is an anthelmintic drug that is used in veterinary medicine to treat parasitic worms (ascarids, whipworms, roundworms, and a single species of tapeworm) in animals. It is also being used by humans in a cancer treatment method called the Joe Tippens protocol.
This medication works by interfering with the formation of microtubules, a protein scaffold that gives cells their shape and structure. It disrupts the movement of cellular components and inhibits cellular division.
Researchers have found that fenbendazole can suppress the growth of human lung adenocarcinoma cells in vitro. It can also reduce tumor size in mice with a KRAS mutation. This suggests that fenbendazole may have multiple cellular targets and can overcome drug resistance.
Anti-bacterial
Researchers have found that fenbendazole, which is used to treat parasitic worms in animals like horses, can also help prevent the spread of cancers. The results of their study, which were published in Scientific Reports, show that the broad-spectrum anti-parasitic drug could be used as a chemotherapeutic agent for human cancers.
The benzimidazole carbamate anthelmintic class has been in wide use for over six decades. These drugs are effective against a large number of parasitic organisms and have few side effects. However, they do have some limitations. These limitations include toxicity to the liver and other organs and resistance to some antibiotics.
Anti-fungal
Fenbendazole belongs to the benzimidazole family of broad-spectrum anti-fungal agents. It is a powerful anthelmintic that has been in use for more than 50 years. It also has an outstanding track record of safety for human use.
Despite its relatively small proportion in the gut microbiome, fungi play important roles in human intestinal homoeostasis and disease pathogenesis. Recent studies have shown that the compositional or morphological balance of gut fungi dictates host protective and pro-inflammatory immune responses. This underlines the concept that a dysbiosis of gut fungi may be one of the underlying causes of disease.
Anti-microbial
Fenbendazole, also known as fenben or Panacur, is an anti-worm medication commonly used to treat parasitic diseases and worms in animals (including roundworms, hookworms, whipworms, and some tapeworms). It belongs to the broad-spectrum benzimidazole carbamate anthelmintic class.
Molecular models suggest that fenbendazole inhibits the growth of bacteria by targeting tubulin, an important component of microtubules. These polymers form the cytoskeleton, which provides shape and structure to cells. This function is similar to the cytotoxic effects of many chemotherapies.
While there is no evidence that fenbendazole can cure cancer, it may be able to help patients with certain types of tumors. This is because fenbendazole inhibits cell proliferation and growth by blocking the production of a protein called GTPase C, which is required for cell growth. fenben for humans